PTPN23 Polyclonal Antibody

Cat.#: 164368

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Product Information

  • Product Name
    PTPN23 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PTPN23
  • Tested applications
    WB
  • Species reactivity
    Mouse, Rat
  • Alternative names
    PTPN23 antibody; HD-PTP antibody; HDPTP antibody; PTP-TD14 antibody; tyrosine-protein phosphatase non-receptor type 23 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1230-1450 of human PTPN23 (NP_056281.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - PTPN23 Polyclonal Antibody

    Western blot - PTPN23 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using PTPN23 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 5s.

  • Background
    Plays a role in sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs) via its interaction with the ESCRT-I complex (endosomal sorting complex required for transport I), and possibly also other ESCRT complexes. May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"