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Product Name
PTBP2 antibody
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Description
PTBP2 Rabbit Polyclonal antibody. Positive WB detected in mouse heart tissue, mouse brain tissue, mouse skeletal muscle tissue. Observed molecular weight by Western-blot: 57-60 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
brPTB antibody; FLJ34897 antibody; PTB antibody; PTB like protein antibody; PTBLP antibody; PTBP2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_021190). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
mouse heart tissue were subjected to SDS PAGE followed by western blot with Catalog No:114260(PTBP2 antibody) at dilution of 1:1000
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Background
PTBP2, also named as NPTB, PTB and PTBLP, is a RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. It may antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. Beside its function in pre-mRNA splicing, PTBP2 plays also a role in the regulation of translation. Isoform 5 has a reduced affinity for RNA. (PMID:11003644) This antibody is specific to PTBP2.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"