Cart 2

PSMC4 antibody

Cat.#: 114391

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    PSMC4 antibody
  • Documents
  • Description
    PSMC4 Rabbit Polyclonal antibody. Positive WB detected in human skeletal muscle tissue, human brain tissue. Positive IF detected in HepG2 cells. Positive IHC detected in human colon cancer tissue. Observed molecular weight by Western-blot: 47 kDa
  • Tested applications
    ELISA, WB, IHC, IF
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    MB67 interacting protein antibody; MIP224 antibody; PSMC4 antibody; Tat binding protein 7 antibody; TBP 7 antibody; TBP7 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of PSMC4 recombinant protein (Accession Number: NM_006503). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

    IF: 1:10-1:100

  • Validations

    human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:114391(PSMC4 antibody) at dilution of 1:500

    human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with Catalog No:114391(PSMC4 antibody) at dilution of 1:500

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:114391(PSMC4 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:114391(PSMC4 antibody) at dilution of 1:50 (under 10x lens)

    Immunofluorescent analysis of HepG2 cells, using PSMC4 antibody Catalog No:114391 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

    Immunofluorescent analysis of HepG2 cells, using PSMC4 antibody Catalog No:114391 at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

  • Background
    PSMC4(proteasome (prosome, macropain) 26S subunit, ATPase, 4) is also named as TBP7, S6, TBP7, MIP224 and belongs to the AAA ATPase family. The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The predicted 458-amino acid TBP7 protein is 57% identical to TBP1 and they can form heterodimers(PMID:8419915).
  • References
    • Yuan F, Ma Y, You P. A novel role of proteasomal β1 subunit in tumorigenesis. Bioscience reports. 33(4):. 2013.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"