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Product Name
PSMB6 antibody
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Description
PSMB6 Rabbit Polyclonal antibody. Positive IHC detected in human colon cancer tissue, human gliomas tissue. Positive WB detected in human brain tissue, HeLa cells, human liver tissue. Observed molecular weight by Western-blot: 25kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
20S proteasome antibody; DELTA antibody; LMPY antibody; Macropain delta chain antibody; Proteasome delta chain antibody; Proteasome subunit beta type 6 antibody; Proteasome subunit Y antibody; PSMB6 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PSMB6 recombinant protein (Accession Number: NM_002798). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114386(PSMB6 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human colon cancer using Catalog No:114386(PSMB6 antibody) at dilution of 1:50 (under 40x lens)
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Background
PSMB6(Proteasome subunit beta type-6) is also named as LMPY, Y and belongs to the peptidase T1B family.The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH.It may also catalyzes basal processing of intracellular antigens.It can be up-regulated in anaplastic thyroid cancer cell lines and down-regulated by IFNG/IFN-gamma (at protein level)(PMID:8066462;15613457).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"