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Product Name
PSD95-Specific,DLG4 antibody
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Description
PSD95-Specific,DLG4 Rabbit Polyclonal antibody. Positive IHC detected in rat brain tissue, mouse brain tissue. Positive WB detected in mouse brain tissue, rat brain tissue. Positive IP detected in mouse brain tissue. Observed molecular weight by Western-blot: 90-95 kDa
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Tested applications
ELISA, IHC, WB, IP
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Disks large homolog 4 antibody; DLG4 antibody; FLJ97752 antibody; FLJ98574 antibody; PSD 95 antibody; PSD95 antibody; SAP 90 antibody; SAP90 antibody; Synapse assOCiated protein 90 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_001365). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IP: 1:200-1:1000
IHC: 1:10-1:100
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Validations
Immunohistochemistry of paraffin-embedded rat brain slide using Catalog No:114297(PSD95-Specific,DLG4 Antibody) at dilution of 1:25
mouse brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:114297(PSD95-Specific,DLG4 Antibody) at dilution of 1:300
IP Result of anti-PSD95-Specific,DLG4 (IP:Catalog No:114297, 4ug; Detection:Catalog No:114297 1:300) with mouse brain tissue lysate 4000ug.
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Background
PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (disks large homolog 4) gene. PSD-95 is a scaffolding protein of the MAGUK protein family, and engages in several vital protein-protein interactions in the brain with its PDZ domains. It has been suggested that PSD-95 is composed of two supramodules, one of which is the PDZ1-2 tandem domain. It plays an important role in synaptic plasticity and the stabilization of synaptic changes during long-term potentiation.
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