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Product Name
PRRT2 Polyclonal Antibody
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Description
Polyclonal antibody to PRRT2
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Tested applications
WB
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Species reactivity
Human, Mouse
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Alternative names
PRRT2 antibody; BFIC2 antibody; BFIS2 antibody; DSPB3 antibody; DYT10 antibody; EKD1 antibody; FICCA antibody; ICCA antibody; IFITMD1 antibody; PKC antibody; proline-rich transmembrane protein 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-130 of human PRRT2 (NP_660282.2).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - PRRT2 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using PRRT2 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 5s.
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Background
As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"