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Product Name
Human S100A7 recombinant protein
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Description
Protein S100-A7, also known as S100 calcium-binding protein A7, Psoriasin, S100A7, and PSOR1, is a secreted protein which belongs to the S-100 family. S100A7 was first isolated from skin involved by psoriasis, which can be induced in cultured squamous epithelial cells. S100A7 is expressed by both normal cultured and malignant keratinocytes and malignant breast epithelial cells within ductal carcinoma in situ, suggesting an association with abnormal pathways of differentiation. S100A7 plays a role in the pathogenesis of inflammatory skin disease, as a chemotactic factor for hematopoietic cells. It also plays a role in early stages of breast tumor progression in association with the development of the invasive phenotype.
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Protein name
Protein S100-A7
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Protein short names
PSOR1; S100A7C; S100A7
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Uniprot ID
P31151
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Gene Name
S100A7; PSOR1; S100A7C
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the native human S100A7 (NP_002954.2) (Met 1-Gln 101) was expressed.
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Protein Species
Human
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Molecular weight
The recombinant human S100A7 consisting of 101 amino acids and migrates as an 11.6 kDa band in SDS-PAGE under reducing conditions as predicted.
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Purity
> 98 % as determined by SDS-PAGE
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Validations
Human S100A7 / PSOR1 Protein SDS-PAGE
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