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Product Name
Human FAM3C / ILEI (Fc Tag) recombinant protein
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Description
FAM3C, also known as ILEI, is a member of the FAM3 family. It can be detected in resent in most secretory epithelia. FAM3C may be involved in retinal laminar formation. It promotes epithelial to mesenchymal transition. A change in expression of FAM3C has been noted in pancreatic cancer-derived cells. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.
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Protein name
Protein FAM3C
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Protein short names
D6WSU176E; FAMILY WITH SEQUENCE SIMILARITY 3; ILEI; INTERLEUKIN-LIKE EMT INDUCER; PREDICTED OSTEOBLAST PROTEIN; PROTEIN FAM3C; MEMBER C; FAM3C; GS3786
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Uniprot ID
Q92520
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Gene Name
FAM3C; ILEI; GS3786
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human FAM3C (Q92520)(Met1-Asp227) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human FAM3C/Fc is a disulfide-linked homodimer. The reduced monomer comprises 444 amino acids and has a predicted molecular mass of 49.2 kDa. The apparent molecular mass of the protein is approximately 53 and 35 kDa in SDS-PAGE under reducing conditions.
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Purity
(73.6+19.1) % as determined by SDS-PAGE
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Validations
Human FAM3C / ILEI Protein (Fc Tag) SDS-PAGE
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