Human PTGDS / L-PGDS (His Tag) recombinant protein

Human PTGDS / L-PGDS (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Prostaglandin-H2 D-isomerase

PTGS3; RP23-47P18.11-006; PGDS; PROSTAGLANDIN D SYNTHASE; 21KDA; PGDS2; RP11-229P13.6; GLUTATHIONE-INDEPENDENT PGD SYNTHASE; L-PGDS; CEREBRIN-28; PROSTAGLANDIN-H2 D-ISOMERASE; PROSTAGLANDIN-D2 SYNTHASE; PGD2 SYNTHASE; BETA-TRACE PROTEIN; LIPOCALIN-TYPE PROSTAGLANDIN-D SYNTHASE; PROSTAGLANDIN D2 SYNTHASE (21 KDA; PDS; GLUTATHIONE-INDEPENDENT PGD SYNTHETASE; LPGDS; BRAIN); PGD2; LIPOCALIN-TYPE PROSTAGLANDIN D SYNTHASE

P41222

PTGDS; PDS

Human Cells

A DNA sequence encoding the human PTGDS (P41222) (Met1-Gln190) was expressed with a polyhistidine tag at the C-terminus.

Human

The recombinant human PTGDS consists of 179 amino acids and predicts a molecular mass of 20.1 KDa. It migrates as an approximately 28 KDa band in SDS-PAGE under reducing conditions.

> 80 % as determined by SDS-PAGE