Anti-Prostaglandin D Synthase Rabbit antibody

Cat.#: 167437

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Product Information

  • Product Name
    Anti-Prostaglandin D Synthase Rabbit antibody
  • Documents
  • Description
    Prostaglandin D Synthase Rabbit polyclonal antibody
  • Tested applications
    WB, IHC-P, ICC/IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    PDS; PGD2; PGDS; LPGDS; PGDS2; L-PGDS antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human Prostaglandin D Synthase
  • Clonality
    Polyclonal
  • Formulation
    Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
  • Storage instructions
    Store at -20°C. Stable for 12 months from date of receipt.
  • Applications

    WB: 1/1000

    IHC: 1/20

    ICC/IF: 1/20

  • Validations

    Western blot detection of Prostaglandin D Synthase in K562,C6,3T3,Hela cell lysates using Prostaglandin D Synthase Rabbit pAb(1:1000 diluted).Predicted band size:21kDa.Observed band size:26kDa.

    Western blot detection of Prostaglandin D Synthase in K562,C6,3T3,Hela cell lysates using Prostaglandin D Synthase Rabbit pAb(1:1000 diluted).Predicted band size:21kDa.Observed band size:26kDa.

  • Background
    Swiss-Prot Acc.P41222.Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-testis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"