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Product Name
PRKCDBP Polyclonal Antibody
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Description
Polyclonal antibody to PRKCDBP
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Tested applications
WB
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Species reactivity
Human, Rat
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Alternative names
CAVIN3 antibody; HSRBC antibody; PRKCDBP antibody; SRBC antibody; cavin-3 antibody; caveolae associated protein 3 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human PRKCDBP
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:200 - 1:1000
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Validations
Western blot - PRKCDBP Polyclonal Antibody
Western blot analysis of extracts of rat kidney, using PRKCDBP antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 1s.
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Background
Regulates the traffic and/or budding of caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in smooth muscle but not in the lung and heart endothelial cells. Regulates the equilibrium between cell surface-associated and cell surface-dissociated caveolae by promoting the rapid release of caveolae from the cell surface. Plays a role in the regulation of the circadian clock. Modulates the period length and phase of circadian gene expression and also regulates expression and interaction of the core clock components PER1/2 and CRY1/2 (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"