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  • PRDM5 Polyclonal Antibody
  • PRDM5 Polyclonal Antibody
  • PRDM5 Polyclonal Antibody
  • PRDM5 Polyclonal Antibody
  • PRDM5 Polyclonal Antibody

PRDM5 Polyclonal Antibody

Cat.#: 166635

Special Price 174.2 USD

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Product Information

  • Product Name
    PRDM5 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PRDM5
  • Tested applications
    WB, IHC, IF
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    PRDM5 antibody; BCS2 antibody; PFM2 antibody; PR/SET domain 5 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human PRDM5 (NP_061169.2).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
  • Validations

    Western blot - PRDM5 Polyclonal Antibody

    Western blot - PRDM5 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using PRDM5 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

    Immunohistochemistry - PRDM5 Polyclonal Antibody

    Immunohistochemistry - PRDM5 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded rat spleen using PRDM5 antibody at dilution of 1:100 (40x lens).

    Immunohistochemistry - PRDM5 Polyclonal Antibody

    Immunohistochemistry - PRDM5 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse liver using PRDM5 antibody at dilution of 1:100 (40x lens).

    Immunohistochemistry - PRDM5 Polyclonal Antibody

    Immunohistochemistry - PRDM5 Polyclonal Antibody

    Immunohistochemistry of paraffin-embedded mouse spleen using PRDM5 antibody at dilution of 1:100 (40x lens).

    Immunofluorescence - PRDM5 Polyclonal Antibody

    Immunofluorescence - PRDM5 Polyclonal Antibody

    Immunofluorescence analysis of A549 cells using PRDM5 antibody . Blue: DAPI for nuclear staining.

  • Background
    Sequence-specific DNA-binding transcription factor. Represses transcription at least in part by recruitment of the histone methyltransferase EHMT2/G9A and histone deacetylases such as HDAC1. Regulates hematopoiesis-associated protein-coding and microRNA (miRNA) genes. May regulate the expression of proteins involved in extracellular matrix development and maintenance, including fibrillar collagens, such as COL4A1 and COL11A1, connective tissue components, such as HAPLN1, and molecules regulating cell migration and adhesion, including EDIL3 and TGFB2. May caused G2/M arrest and apoptosis in cancer cells.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"