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Product Name
PRDM4 antibody
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Description
PRDM4 Rabbit Polyclonal antibody. Positive WB detected in mouse pancreas tissue, COLO 320 cells. Observed molecular weight by Western-blot: 88kd
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Tested applications
ELISA, WB
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
PRDM4 antibody; PR domain containing protein 4 antibody; PR domain containing 4 antibody; PFM1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PRDM4 recombinant protein (Accession Number: NM_012406). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
mouse pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:114174(PRDM4 antibody) at dilution of 1:500
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Background
The PRDM family members are characterized by the presence of a PR (positive regulatory) domain and multiple zinc finger (ZnFg) domains. The PR domain defines a family of transcription factors involved in cell differentiation and tumorigenesis. PRDM proteins are either epigenetic modifiers in their own right or else they recruit third party chromatin modifiers - e.g. histone deacetylases (HDACs), histone lysine MTases or histone arginine MTases - to regulate cell type-specific gene expression in various tissues (PRDM4 as an HDAC-associated transcriptional repressor that modulates cell cycle progression.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"