-
Product Name
PRDM16 Polyclonal Antibody
- Documents
-
Description
Polyclonal antibody to PRDM16
-
Tested applications
WB
-
Species reactivity
Human, Mouse
-
Alternative names
PRDM16 antibody; CMD1LL antibody; KMT8F antibody; LVNC8 antibody; MEL1 antibody; PFM13 antibody; PR/SET domain 16 antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: A synthetic peptide of human PRDM16
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide, pH7.3.
-
Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
-
Applications
WB 1:500 - 1:1000
-
Validations
Western blot - PRDM16 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using PRDM16 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
-
Background
Binds DNA and functions as a transcriptional regulator. Functions in the differentiation of brown adipose tissue (BAT) which is specialized in dissipating chemical energy in the form of heat in response to cold or excess feeding while white adipose tissue (WAT) is specialized in the storage of excess energy and the control of systemic metabolism. Together with CEBPB, regulates the differentiation of myoblastic precursors into brown adipose cells. Functions also as a repressor of TGF-beta signaling. Isoform 4 may regulate granulocytes differentiation.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"