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Product Name
PRC1 antibody
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Description
PRC1 Rabbit Polyclonal antibody. Positive WB detected in HEK-293T cells, HeLa cells, HepG2 cells, MCF-7 cells. Observed molecular weight by Western-blot: 67 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
ASE1 antibody; PRC1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PRC1 recombinant protein (Accession Number: BC005140). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
HEK-293T cells were subjected to SDS PAGE followed by western blot with Catalog No:114168(PRC1 Antibody) at dilution of 1:600
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Background
PRC1 is involved in cytokinesis. PRC1 is at high level during S and G2/M and drop dramatically after cell exit mitosis and enter G1. PRC1 is located in the nucleus during interphase, and becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. PRC1 is a good substrate for several cyclin-dependent kinases (CDKs) in vitro and is phosphorylated in vivo at sites that are phosphorylated by CDK in vitro, suggesting that PRC1 is an in vivo CDK substrate.
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