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Product Name
PPM1A antibody
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Description
PPM1A Rabbit Polyclonal antibody. Positive WB detected in human liver tissue, HeLa cells, HepG2 cells, human heart tissue. Observed molecular weight by Western-blot: 42 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ42306 antibody; PP2C ALPHA antibody; PP2CA antibody; PPM1A antibody; PPPM1A antibody; Protein phosphatase 1A antibody; Protein phosphatase IA antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PPM1A recombinant protein (Accession Number: XM_011536879). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
human liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:114132(PPM1A antibody) at dilution of 1:900
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Background
PPM1A(Protein phosphatase 1A) is also named as PPPM1A and belongs to the PP2C family. It is a serine/threonine protein phosphatase that is essential for regulating cellular stress responses in eukaryotes. PPM1A plays an important role in tumor suppression and that it negatively controls many signaling pathways which are critical for trophoblast invasion.(PMID:19404668). This protein distributes in both the cytoplasm and nucleus of mammalian cells(PMID:9003755). It has 2 isoforms produced by alternative splicing.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"