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Product Name
PPCS antibody
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Description
PPCS Rabbit Polyclonal antibody. Positive IHC detected in human kidney tissue, human lung tissue, human ovary tissue, human placenta tissue, human spleen tissue, human testis tissue. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 34kd
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
COAB antibody; FLJ11838 antibody; PPC synthetase antibody; PPCS antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PPCS recombinant protein (Accession Number: NM_024664). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:114118(PPCS antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human kidney using Catalog No:114118(PPCS antibody) at dilution of 1:100 (under 10x lens)
Immunohistochemical of paraffin-embedded human kidney using Catalog No:114118(PPCS antibody) at dilution of 1:100 (under 40x lens)
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Background
PPCS(Phosphopantothenate--cysteine ligase) is also named as COAB and belongs to the PPC synthetase family. It catalyzes the first step in the biosynthesis of coenzyme A from vitamin B5, where cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. It can be exsit as a homodimer(PMID:12906824).
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