POMGNT2 Polyclonal Antibody

Cat.#: 164897

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Product Information

  • Product Name
    POMGNT2 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to POMGNT2
  • Tested applications
    IF
  • Species reactivity
    Human
  • Alternative names
    POMGNT2 antibody; AGO61 antibody; C3orf39 antibody; GTDC2 antibody; MDDGA8 antibody; protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 301-580 of human POMGNT2 (NP_116195.2).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    IF 1:20 - 1:50
  • Validations

    Immunofluorescence - POMGNT2 Polyclonal Antibody

    Immunofluorescence - POMGNT2 Polyclonal Antibody

    Immunofluorescence analysis of A549 cells using POMGNT2 antibody . Blue: DAPI for nuclear staining.

  • Background
    O-linked mannose beta-1,4-N-acetylglucosaminyltransferase that transfers UDP-N-acetyl-D-glucosamine to the 4-position of the mannose to generate N-acetyl-D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"