PNPLA3 antibody

PNPLA3 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PNPLA3 Rabbit Polyclonal antibody. Positive IP detected in HepG2 cells. Positive WB detected in HepG2 cells, human adipose tissue, Jurkat cells. Observed molecular weight by Western-blot: 53 kDa

ELISA, WB, IP

Human; other species not tested.

Acylglycerol O acyltransferase antibody; Adiponutrin antibody; ADPN antibody; C22orf20 antibody; iPLA(2)epsilon antibody; iPLA2 epsilon antibody; PNPLA3 antibody

Rabbit IgG

This antibody was obtained by immunization of PNPLA3 recombinant protein (Accession Number: BC014449). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PNPLA3(patatin-like phospholipase domain-containing protein 3), also named as ADPN, C22orf20, alternatively referred to as adiponutrin, encodes a 481-amino acid protein of 54 kDa that belongs to the patatin-like phospholipase domain-containing family. Despite the apparent absence of a membrane-spanning domain, PNPLA3 is tightly associated with membranes and it may be targeted specifically to regions of the ER membrane that are destined to become nascent lipid droplets(PMID:22338072). It is a multifunctional enzyme which has both triacylglycerol lipase and acylglycerol O-acyltransferase activities. Genetic variations in PNPLA3 are a cause of susceptibility to non-alcoholic fatty liver disease type 1 (NAFLD1). It has 2 isoforms produced by alternative splicing.