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Product Name
PNOC Polyclonal Antibody
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Description
Polyclonal antibody to PNOC
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Tested applications
WB, IF
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Species reactivity
Human
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Alternative names
PNOC antibody; N/OFQ antibody; NOP antibody; OFQ antibody; PPNOC antibody; ppN/OFQ antibody; prepronociceptin antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-176 of human PNOC (NP_006219.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IF 1:50 - 1:100 -
Validations
Immunofluorescence - PNOC Polyclonal Antibody
Immunofluorescence analysis of U2OS cells using PNOC antibody . Blue: DAPI for nuclear staining.
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Background
Nociceptin: Ligand of the opioid receptor-like receptor OPRL1. It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. May be involved in neuronal differentiation and development.; Nocistatin: Blocks nociceptin action in pain transmission by inhibiting nociceptin-induced hyperalgesia and allodynia.; Orphanin FQ2: Has potent analgesic activity.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"