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PMP2 antibody

Cat.#: 114027

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Product Information

  • Product Name
    PMP2 antibody
  • Documents
  • Description
    PMP2 Rabbit Polyclonal antibody. Positive IHC detected in human gliomas. Positive WB detected in mouse testis tissue, human brain tissue. Observed molecular weight by Western-blot: 15-20 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    human, mouse, rat; other species not tested.
  • Alternative names
    PMP2 antibody; FABP8 antibody; MP2 antibody; Myelin P2 protein antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of PMP2 recombinant protein (Accession Number: NM_002677). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:114027(PMP2 antibody) at dilution of 1:1000

    mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:114027(PMP2 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:114027(PMP2 antibody) at dilution of 1:100 (under 10x lens)

    Immunohistochemical of paraffin-embedded human gliomas using Catalog No:114027(PMP2 antibody) at dilution of 1:100 (under 10x lens)

  • Background
    PMP2 (peripheral myelin protein-2, also known as P2) is one of the major proteins of peripheral myelin and appears to be related to the transport of fatty acids or the metabolism of myelin lipids.P2 constitutes up to 15% of total protein of peripheral nervous system (PNS) myelin. It is also present in small amounts in central nervous system (CNS) myelin, being abundant in spinal cord and brain stem myelin. As a structural protein, P2 is thought to stabilize the myelin membranes.
  • References
    • Monticone M, Daga A, Candiani S. Identification of a novel set of genes reflecting different in vivo invasive patterns of human GBM cells. BMC cancer. 12:358. 2012.
    • Zenker J, Stettner M, Ruskamo S. A role of peripheral myelin protein 2 in lipid homeostasis of myelinating Schwann cells. Glia. 62(9):1502-12. 2014.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"