PLXNA4 Polyclonal Antibody
Polyclonal antibody to PLXNA4
PLXNA4 antibody; FAYV2820 antibody; PLEXA4 antibody; PLXNA4A antibody; PLXNA4B antibody; PRO34003 antibody; plexin-A4 antibody
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-220 of human PLXNA4 (NP_861440.2).
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Store at -20℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:2000
Western blot - PLXNA4 Polyclonal Antibody
Western blot analysis of extracts of rat lung, using PLXNA4 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 10s.
Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity).
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