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Product Name
PLXDC2 antibody
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Description
PLXDC2 Rabbit Polyclonal antibody. Positive WB detected in A375 cells, HEK-293 cells, HeLa cells. Observed molecular weight by Western-blot: 54 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
FLJ14623 antibody; plexin domain containing 2 antibody; PLXDC2 antibody; TEM7R antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PLXDC2 recombinant protein (Accession Number: NM_001282736). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
A375 cells were subjected to SDS PAGE followed by western blot with Catalog No:114017(PLXDC2 antibody) at dilution of 1:500
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Background
PLXDC2 (Plexin-domain containing 2), also named tumor endothelial marker 7-related protein (TEM7R), is a single-pass type I membrane protein with some homology to nidogen and to plexins. PLXDC2 is located in tumor endothelium and plays a role in tumor angiogenesis. Three isoforms of PLXDC2 produced by alternative splicing have been described. Recent finding revealed that PLXDC2 is a mitogen for neural progenitors and functions as a novel regulator of the development of different brain regions, suggesting its role in coordinating proliferation and differentiation in the developing nervous system.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"