PLG Polyclonal Antibody
Polyclonal antibody to PLG
PLG antibody; plasminogen antibody
Antigen: A synthetic peptide of human PLG
PBS with 0.02% sodium azide, pH7.3.
Store at 4℃. Avoid freeze / thaw cycles.
WB 1:500 - 1:1000
Western blot - PLG Polyclonal Antibody
Western blot analysis of extracts of human blood plasma, using PLG antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.; Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
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