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  • PLG Polyclonal Antibody

PLG Polyclonal Antibody

Cat.#: 166582

Special Price 290.3 USD

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Product Information

  • Product Name
    PLG Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PLG
  • Tested applications
    WB
  • Species reactivity
    Human
  • Alternative names
    PLG antibody; plasminogen antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human PLG
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, pH7.3.
  • Storage instructions
    Store at 4℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:1000
  • Validations

    Western blot - PLG Polyclonal Antibody

    Western blot - PLG Polyclonal Antibody

    Western blot analysis of extracts of human blood plasma, using PLG antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated by CSPG4. Binds to cells.; Angiostatin is an angiogenesis inhibitor that blocks neovascularization and growth of experimental primary and metastatic tumors in vivo.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"