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Product Name
PLAA antibody
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Description
PLAA Mouse Monoclonal antibody. Positive WB detected in A431 cells. Observed molecular weight by Western-blot: 72-74 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
DOA1 antibody; FLJ11281 antibody; FLJ12699 antibody; PLA2P antibody; PLAA antibody; PLAP antibody
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Isotype
Mouse IgG1
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Preparation
This antibody was obtained by immunization of PLAA recombinant protein (Accession Number: NM_001031689). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
A431 cells were subjected to SDS PAGE followed by western blot with Catalog No:107475(PLAA antibody) at dilution of 1:1000
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Background
Phospholipase A-2-activating protein (PLAA), also named PLAP, can interact with ubiquitin and is involved in the maintenance of ubiquitin levels. PLAA contains multiple consensus domains including WD repeats, PFU domain and PUL domain. Although the function of PLAA remains unclear, ubiquitin binding of PLAA might be the central role that connects ubiquitination and degradation in ERAD. Recent finding revealed that PLAA served as a novel nociveptive mediator after incision, and its expression level is regulated by miR-203.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"