PKC alpha antibody

PKC alpha antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PKC alpha Rabbit Polyclonal antibody. Positive IHC detected in human thyroid cancer tissue. Positive IF detected in NIH/3T3 cells. Positive WB detected in Jurkat cells, NIH/3T3 cells. Positive IP detected in NIH/3T3 cells. Observed molecular weight by Western-blot: 77 kDa

ELISA, WB, IP, IHC, IF

Human, Mouse; other species not tested.

AAG6 antibody; PKC A antibody; PKC alpha antibody; PKCA antibody; PRKACA antibody; PRKCA antibody; Protein kinase C alpha type antibody; protein kinase C antibody; alpha antibody

Rabbit IgG

This antibody was obtained by immunization of PKC alpha recombinant protein (Accession Number: AK055431). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PRKCA is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

• Jiang L, Cui Y, Luan J, Zhou X, Zhou X, Han J. A comparative proteomics study on matrix vesicles of osteoblast-like Saos-2 and U2-OS cells. Intractable & rare diseases research. 2(2):59-62. 2013.