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Product Name
PGRMC2 antibody
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Description
PGRMC2 Mouse Monoclonal antibody. Positive WB detected in HeLa cells. Observed molecular weight by Western-blot: 24+28KD
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse; other species not tested.
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Alternative names
DG6 antibody; PGRMC2 antibody; PMBP antibody
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Isotype
Mouse IgG2a
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Preparation
This antibody was obtained by immunization of PGRMC2 recombinant protein (Accession Number: NM_006320). Purification method: Protein A purified.
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Clonality
Monoclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107468(PGRMC2 antibody) at dilution of 1:1000
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Background
Membrane-associated progesterone receptor component 2 (PGRMC2), also known as DG6 or PMBP, belongs to the cytochrome b5 family. The gene of PGRMC2 maps to chromosome 4q26, and encodes a 223-amino acid single-pass membrane protein with a cytochrome b5 heme-binding domain in its cytoplasmic domain. PGRMC2 is highly homologous to PGRMC1. PGRMC2 might play a role in cancer.
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References
- Ye X, Zhang Y, He B, Meng Y, Li Y, Gao Y. Quantitative proteomic analysis identifies new effectors of FOXM1 involved in breast cancer cell migration. International journal of clinical and experimental pathology. 8(12):15836-44. 2015.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"