PGAM1 antibody

PGAM1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PGAM1 Rabbit Polyclonal antibody. Positive IHC detected in human brain tissue. Positive WB detected in human brain tissue, A549 cells, HepG2 cells, L02 cells, MCF7 cells, mouse liver tissue, rat brain tissue, rat liver tissue. Observed molecular weight by Western-blot: 29kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

BPG dependent PGAM 1 antibody; PGAM B antibody; PGAM1 antibody; PGAMA antibody; Phosphoglycerate mutase 1 antibody

Rabbit IgG

This antibody was obtained by immunization of PGAM1 recombinant protein (Accession Number: NM_002629). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PGAM1(phosphoglycerate mutase 1) is also named as PGAMA,PGAM-B and belongs to the phosphoglycerate mutase family. Phosphoglycerate mutase is widely distributed in mammalian tissues where it catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. The homodimer PGAM1 is expressed mainly in liver, kidney, brain and overexpressed in a variety of human cancers, including breast carcinoma, colorectal cancer, lung cancer, prostate cancer, oral squamous cell carcinoma, esophageal squamous cell carcinomas and also associated with certain virus infection. PGAM1 could be developed as a useful diagnostic biomarker, as well as a potential therapeutic target for hepatocellular carcinoma.(PMID:20403181). This antibody is specific to PGAM1.

• Sun L, Song L, Wan Q. cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions. Cell research. 25(4):429-44. 2015.