PFTK1 antibody

PFTK1 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PFTK1 Rabbit Polyclonal antibody. Positive WB detected in HeLa cells, mouse brain tissue, SH-SY5Y cells. Positive IHC detected in human kidney tissue, mouse brain tissue. Observed molecular weight by Western-blot: 48-53kd

ELISA, WB, IHC

Human,Mouse,Rat; other species not tested.

CDK14 antibody; hPFTAIRE1 antibody; KIAA0834 antibody; PFTAIRE protein kinase 1 antibody; PFTAIRE1 antibody; PFTK1 antibody

Rabbit IgG

This antibody was obtained by immunization of PFTK1 recombinant protein (Accession Number: NM_012395). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

PFTK1 is a Cdc2-related protein kinase, also named as PFTAIRE1, CDK14 and belongs to the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It acts as a cyclin-dependent kinases that regulates cell cycle progression and cell proliferation. The PFTK1 protein shows high homology with mouse Pftaire1, a Cdc2-related protein expressed primarily in the postnatal and adult nervous system(PMID:9202329). The protein contains 2 predicted nuclear localization signals that the N-terminal nuclear localization signals do not play a role in vivo(PMID:11313143). It has 3 isoforms produced by alternative splicing. This antibody is specific to PFTK1.

• Pollack D, Xiao Y, Shrivasatava V. CDK14 expression is down-regulated by cigarette smoke in vivo and in vitro. Toxicology letters. 234(2):120-30. 2015.