PEX5 antibody

PEX5 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PEX5 Mouse Monoclonal antibody. Positive WB detected in pig brain tissue, fetal human brain tissue. Positive IHC detected in human liver tissue, human kidney tissue. Observed molecular weight by Western-blot: 70 kDa

ELISA, WB, IHC

Human, Pig, Rat; other species not tested.

FLJ50634 antibody; FLJ50721 antibody; FLJ51948 antibody; Peroxin 5 antibody; Peroxisome receptor 1 antibody; PEX5 antibody; PTS1 BP antibody; PTS1 receptor antibody; PTS1R antibody; PXR1 antibody

Mouse IgG1

This antibody was obtained by immunization of PEX5 recombinant protein (Accession Number: XM_047429267). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

The peroxisomal targeting signal type1 (PTS1) receptor, PEX5, is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins, respectively, and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic, partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10, PEX12, PEX13, and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS), which is a lethal peroxisome biogenesis disorder.