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Product Name
Human ACOX1 / AOX (His Tag) recombinant protein
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Description
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. Isoform 1 shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length. Isoform 2 is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Isoform 2 is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
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Protein name
Peroxisomal acyl-coenzyme A oxidase 1
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Protein short names
ACOX; SCOX; PALMCOX; D130055E20RIK; AI042784; RP23-42F6.11-001; PAOX; MGC1198; AOX
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Uniprot ID
Q15067
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Gene Name
ACOX1; ACOX
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human ACOX1 (AAH08767.1) (Met 1-Leu 660) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human ACOX1consists of 679 amino acids and has a calculated molecular mass of 76.7 kDa. It migrates as an approximately 60 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 92 % as determined by SDS-PAGE
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Validations
Human ACOX1 / aox Protein (His Tag) SDS-PAGE
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