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Product Name
Human PPIL2 (aa 280-457, His Tag) recombinant protein
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Description
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins (By similarity). May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance (PubMed:15946952). May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423).
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Protein name
Peptidyl-prolyl cis-trans isomerase-like 2
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Protein short names
ROTAMASE PPIL2; CYCLOPHILIN-LIKE PROTEIN CYP-60; CYP-60; C130078A06RIK; CYC4; 1700016N17RIK; 4930511F14RIK; PEPTIDYLPROLYL CIS-TRANS ISOMERASE; CYCLOPHILIN-60; UBOX7; PEPTIDYL-PROLYL CIS-TRANS ISOMERASE-LIKE 2; PPIASE; PPIL2; CYCLOPHILIN; 0610009L05RIK; PEPTIDYLPROLYL ISOMERASE (CYCLOPHILIN)-LIKE 2; HCYP-60; CYP60; AA589416; 4921520K19RIK; 60KDA
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Uniprot ID
Q13356
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Gene Name
PPIL2
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human PPIL2 (Q13356-2) (Gly280-Pro457) was expressed with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PPIL2 consists of 193 amino acids and predicts a molecular mass of 21.9 KDa. It migrates as an approximately 24 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human PPIL2 Protein (aa 280-457, His Tag) SDS-PAGE
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