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Anti-PPIL2 antibody

Cat.#: 104491

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Product Information

  • Product Name
    Anti-PPIL2 antibody
  • Documents
  • Description
    Rabbit polyclonal to PPIL2
  • Tested applications
    ELISA, IHC-P
  • Species reactivity
    Human PPIL2
  • Alternative names
    PPIase antibody; CYC4 antibody; CYP60 antibody; UBOX7 antibody; Cyp-60 antibody; hCyP-60 antibody; CYC4 antibody; AA589416 antibody; 0610009L05Rik antibody; 1700016N17Rik antibody; 4921520K19Rik antibody; 4930511F14Rik antibody; C130078A06Rik antibody; PPIase antibody; 0610009L05Rik antibody; 1700016N17Rik antibody; 4921520K19Rik antibody; 4930511F14Rik antibody; 60kDa antibody; AA589416 antibody; C130078A06Rik antibody; CYC4 antibody; cyclophilin antibody; cyclophilin-60 antibody; cyclophilin-60 antibody; cyclophilin-like protein Cyp-60 antibody; cyclophilin-like protein CyP-60 antibody; CYP60 antibody; Cyp-60 antibody; hCyP-60 antibody; peptidylprolyl cis-trans isomerase antibody; peptidyl-prolyl cis-trans isomerase-like 2 antibody; peptidyl-prolyl cis-trans isomerase-like 2 antibody; peptidylprolyl isomerase (cyclophilin)-like 2 antibody; peptidylprolyl isomerase (cyclophilin)-like 2 antibody; Ppil2 antibody; PPIL2 antibody; rotamase PPIL2 antibody; rotamase PPIL2 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    Produced in rabbits immunized with purified, recombinant Human PPIL2 (rh PPIL2; Q13356-2; Gly280-Pro457). PPIL2 specific IgG was purified by Human PPIL2 affinity chromatography.
  • Clonality
    Polyclonal
  • Formulation
    0.2 μm filtered solution in PBS
  • Storage instructions
    This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.
    Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
  • Applications

    ELISA: 0.1-0.2 μg/mL

    This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect Human PPIL2. The detection limit for Human PPIL2 is <0.039 ng/well.

    IHC-P: 0.1-1 μg/mL

    IP: 1-4 μg/mg of lysate

  • Validations

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunoprecipitation

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    Immunochemical staining of human PPIL2 in human testis with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    Immunochemical staining of human PPIL2 in human pancreas with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    Immunochemical staining of human PPIL2 in human liver with rabbit polyclonal antibody (0.5 µg/mL, formalin-fixed paraffin embedded sections).

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

    PPIL2 Antibody, Rabbit PAb, Antigen Affinity Purified, Immunohistochemistry

  • Background
    PPIL2, is an enzyme which belongs to the cyclophilin family. The cyclophilins are peptidylprolyl isomerases and are highly conserved ubiquitous. They play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. PPIL2 interacts with the proteinase inhibitor eglin c and is localized in the nucleus. It contains 1 PPIL2 cyclophilin-type domain and 1 U-box domain. PPIL2 accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
  • References
    • Grouse LH. et al., 2003, Proc Natl Acad Sci. 99 (26): 16899-903.
    • Lennon G. et al., 1997, Genome Res. 6 (9): 791-806.
    • Payan DG. et al., 1996, Biochem J. 314 (1): 313-9.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"