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Product Name
Pepsinogen II antibody
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Description
Pepsinogen II Rabbit Polyclonal antibody. Positive WB detected in human stomach tissue. Observed molecular weight by Western-blot: 42kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Gastricsin antibody; Pepsinogen C antibody; Pepsinogen II antibody; PEPSINOGEN antibody; GROUP II antibody; PGC antibody; Progastricsin antibody; progastricsin (pepsinogen C) antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Pepsinogen II recombinant protein (Accession Number: NM_002630). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
human stomach tissue were subjected to SDS PAGE followed by western blot with Catalog No:113709(PGC antibody) at dilution of 1:800
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Background
Pepsinogen Iialso known as progastricsin or PGC(pepsinogen C), is an aspartic protease expressed primarily in gastric chief cells and is a novel marker of type 2 cells with advantages over many of the current markers used to identify type 2 cells in the developing lung(PMID:14578117). It is involved in proteolysis and peptidolysis. This protein has 2 isoforms produced by alternative splicing.
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