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Product Name
PDE9A antibody
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Description
PDE9A Rabbit Polyclonal antibody. Positive WB detected in mouse testis tissue, mouse skeletal muscle tissue. Positive IHC detected in human prostate cancer tissue. Observed molecular weight by Western-blot: 50 kDa
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Tested applications
ELISA, IHC, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
HSPDE9A2 antibody; PDE9A antibody; phosphodiesterase 9A antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PDE9A recombinant protein (Accession Number: NM_001001567). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human prostate cancer using Catalog No:113671(PDE9A antibody) at dilution of 1:50 (under 10x lens)
mouse testis tissue were subjected to SDS PAGE followed by western blot with Catalog No:113671(PDE9A Antibody) at dilution of 1:300
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Background
Cyclic nucleotide phosphodiesterases (PDEs), which hydrolyze the intracellular second messengers cAMP and cGMP to their corresponding monophosphates, play an important role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. PDE9A plays a role in signal transduction by regulating the intracellular concentration of these cyclic nucleotides. Multiple transcript variants encoding several different isoforms have been found for this gene. This protein has 16 isoforms with the MW between 44 kDa and 65 kDa.
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