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Product Name
PDE6C antibody
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Description
PDE6C Rabbit Polyclonal antibody. Positive WB detected in Y79 cells. Observed molecular weight by Western-blot: 52 kDa; 99 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human; other species not tested.
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Alternative names
cGMP phosphodiesterase 6C antibody; PDE6C antibody; PDEA2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Peptide (Accession Number: NM_006204). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
Y79 cells were subjected to SDS PAGE followed by western blot with Catalog No:113667(PDE6C antibody) at dilution of 1:200
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Background
PDE6C, also named as PDEA2, belongs to the cyclic nucleotide phosphodiesterase family. It catalyze the reaction: Guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. Defects in PDE6C are the cause of cone dystrophy type 4 (COD4). Mutations in the PDE6C gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase as a cause of autosomal recessive achromatopsia.(PMID:19887631) This antibody is specific to PDE6C.
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