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Product Name
PCYOX1 antibody
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Description
PCYOX1 Rabbit Polyclonal antibody. Positive IHC detected in human colon tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
KIAA0908 antibody; PCL1 antibody; PCYOX1 antibody; Prenylcysteine lyase antibody; prenylcysteine oxidase 1 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PCYOX1 recombinant protein (Accession Number: NM_016297). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human colon using Catalog No:113758(PCYOX1 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human colon using Catalog No:113758(PCYOX1 antibody) at dilution of 1:50 (under 40x lens)
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Background
PCYOX1(Prenylcysteine oxidase 1) is also named as KIAA0908, PCL1, prenylcysteine lyase and belongs to the prenylcysteine oxidase family. The deduced 505-amino acid protein contains a predicted signal sequence, several transmembrane regions, and four potential N-glycosylation sites. It is a glycosylated enzyme involved in prenylated protein catabolism, releasing a free cysteine and a hydrophobic isoprenoid product. Immunofluorescence studies of PCYOX1 showed a nonnuclear punctate pattern, and PCYOX1 colocalized with lysosomal marker LAMP1 in HEK293 cells(PMID:10585463). The enzyme is isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa(PMID:9287348).
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