-
Product Name
PCMT1 antibody
- Documents
-
Description
PCMT1 Rabbit Polyclonal antibody. Positive WB detected in HEK-293 cells, HeLa cells, human testis tissue, Raji cells. Positive IHC detected in human pancreas tissue. Observed molecular weight by Western-blot: 25kd
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
PCMT1 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of PCMT1 recombinant protein (Accession Number: NM_001360452). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:113742(PCMT1 antibody) at dilution of 1:1000
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:113742(PCMT1 antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human pancreas using Catalog No:113742(PCMT1 antibody) at dilution of 1:50 (under 40x lens)
-
Background
PCMT1 represents protein-L-isoaspartate (D-aspartate) O-methyltransferase
-
References
- Wägner AM, Cloos P, Bergholdt R. Post-translational protein modifications in type 1 diabetes: a role for the repair enzyme protein-L-isoaspartate (D-aspartate) O-methyltransferase? Diabetologia. 50(3):676-81. 2007.
- Yan G, Qin Q, Yi B. Protein-L-isoaspartate (D-aspartate) O-methyltransferase protects cardiomyocytes against hypoxia induced apoptosis through inhibiting proapoptotic kinase Mst1. International journal of cardiology. 168(4):3291-9. 2013.
- Föcking M, Dicker P, English JA, Schubert KO, Dunn MJ, Cotter DR. Common proteomic changes in the hippocampus in schizophrenia and bipolar disorder and particular evidence for involvement of cornu ammonis regions 2 and 3. Archives of general psychiatry. 68(5):477-88. 2011.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"