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Product Name
PCDHA2 antibody
- Documents
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Description
PCDHA2 Rabbit Polyclonal antibody. Positive WB detected in human brain tissue, HeLa cells, human heart tissue, Raji cells. Positive IP detected in HeLa cells. Observed molecular weight by Western-blot: 80 kDa
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Tested applications
ELISA, WB, IP
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Species reactivity
Human; other species not tested.
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Alternative names
PCDH alpha 2 antibody; PCDH ALPHA2 antibody; PCDHA2 antibody; protOCadherin alpha 2 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of PCDHA2 recombinant protein (Accession Number: NM_031496). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:1000
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Validations
human brain tissue were subjected to SDS PAGE followed by western blot with Catalog No:113693(PCDHA2 antibody) at dilution of 1:800
IP Result of anti-PCDHA2 (IP:Catalog No:113693, 3ug; Detection:Catalog No:113693 1:300) with HeLa cells lysate 4650ug.
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Background
Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHA2 (protocadherin alpha 2) is a single-pass type I membrane protein containing 6 cadherin domains. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"