-
Product Name
PBX3 antibody
- Documents
-
Description
PBX3 Rabbit Polyclonal antibody. Positive IP detected in HL-60 cells. Positive WB detected in human lung tissue. Positive IHC detected in human lung cancer tissue. Observed molecular weight by Western-blot: 47 kDa
-
Tested applications
ELISA, WB, IHC, IP
-
Species reactivity
Human,Mouse,Rat; other species not tested.
-
Alternative names
Homeobox protein PBX3 antibody; PBX3 antibody; pre B cell leukemia homeobox 3 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of PBX3 recombinant protein (Accession Number: BC016977). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:200-1:2000
IP: 1:200-1:2000
IHC: 1:20-1:200
-
Validations
human lung tissue were subjected to SDS PAGE followed by western blot with Catalog No:113615(PBX3 antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:113615(PBX3 antibody) at dilution of 1:50 (under 10x lens)
IP Result of anti-PBX3 (IP:Catalog No:113615, 4ug; Detection:Catalog No:113615 1:500) with HL-60 cells lysate 3040ug.
-
Background
PBX3, also named as Pre-B-cell leukemia transcription factor 3, is a 434 amino acid protein ,which contains 1 homeobox DNA-binding domain and belongs to the TALE/PBX homeobox family. PBX3 localizes in the nucleus and as a transcriptional activator that binds the sequence 5'-ATCAATCAA-3'. PBX3 is ubiquitously expressed in many tissues.
-
References
- Li Y, Sun Z, Zhu Z, Zhang J, Sun X, Xu H. PBX3 is overexpressed in gastric cancer and regulates cell proliferation. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. 35(5):4363-8. 2014.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"