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  • PARL Polyclonal Antibody
  • PARL Polyclonal Antibody

PARL Polyclonal Antibody

Cat.#: 165753

Special Price 174.2 USD

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Product Information

  • Product Name
    PARL Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PARL
  • Tested applications
    WB, IF
  • Species reactivity
    Human
  • Alternative names
    PARL antibody; PRO2207 antibody; PSARL antibody; PSARL1 antibody; PSENIP2 antibody; RHBDS1 antibody; presenilin associated rhomboid like antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human PARL (NP_001032728.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • Validations

    Western blot - PARL Polyclonal Antibody

    Western blot - PARL Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using PARL antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

    Immunofluorescence - PARL Polyclonal Antibody

    Immunofluorescence - PARL Polyclonal Antibody

    Immunofluorescence analysis of U2OS cells using PARL antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

  • Background
    Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain.
  • References

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"