PARD6A Polyclonal Antibody

Cat.#: 164002

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Product Information

  • Product Name
    PARD6A Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PARD6A
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse
  • Alternative names
    PARD6A antibody; PAR-6A antibody; PAR6 antibody; PAR6C antibody; PAR6alpha antibody; TAX40 antibody; TIP-40 antibody; partitioning defective 6 homolog alpha antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic peptide of human PARD6A
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:2000
  • Validations

    Western blot - PARD6A Polyclonal Antibody

    Western blot - PARD6A Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using PARD6A antibody at 1:200 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.

  • Background
    Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Regulates centrosome organization and function. Essential for the centrosomal recruitment of key proteins that control centrosomal microtubule organization.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"