PAR2 antibody

PAR2 antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

PAR2 Rabbit Polyclonal antibody. Positive WB detected in mouse colon tissue. Observed molecular weight by Western-blot: 50-55kd

ELISA, WB

Human,Mouse,Rat; other species not tested.

F2RL1 antibody; G protein coupled receptor 11 antibody; GPR11 antibody; PAR 2 antibody; PAR2 antibody; Thrombin receptor like 1 antibody

Rabbit IgG

This antibody was obtained by immunization of PAR2 recombinant protein (Accession Number: NM_005242). Purification method: Antigen affinity purified.

Polyclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

Proteinase-activated receptors (PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs include four members: PAR1, PAR2, PAR3 and PAR4. PAR2, also known as F2RL1, is expressed in epithelial cells (e.g., lung, gastrointestinal tract), endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. PAR2 knockout mice and PAR2 agonists and antagonists have implicated PAR2 as a promising target in inflammatory conditions; respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction; and cancers. (PMID:23895492)