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Product Name
Pancreatic Lipase antibody
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Description
Pancreatic Lipase Rabbit Polyclonal antibody. Positive WB detected in human pancreas tissue, mouse pancreas tissue. Positive IHC detected in human pancreas cancer tissue, human pancreas tissue. Observed molecular weight by Western-blot: 52 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
Lipase antibody; Pancreatic Lipase antibody; PNLIP antibody; PTL antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of Pancreatic Lipase recombinant protein (Accession Number: NM_000936). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
human pancreas tissue were subjected to SDS PAGE followed by western blot with Catalog No:113568(PNLIP antibody) at dilution of 1:500
Immunohistochemical of paraffin-embedded human pancreas cancer using Catalog No:113568(PNLIP antibody) at dilution of 1:50 (under 40x lens)
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Background
The pancreatic triacylglycerol lipase precursor (PNLIP), a 56 kDa protein secreted by the pancreas that is essential for the hydrolysis and absorption of long-chain triglyceride fatty acids in the intestine is located ?1 Mb upstream from the chromosome 10 peak(PMID:17890784). It is also named as PL, PTL and belongs to the AB hydrolase superfamily. It may potentially be involved in the pathophysiology of traumatic brain injury and may be implicated in the proliferation of astrocytes and the recovery of neurological outcomes(PMID:19760487). The full length protein has a signal peptide with 16 amino acid and a glycosylation site.
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