-
Product Name
Pamrevlumab reference antibody
- Documents
-
Description
Anti-CCN2 / CTGF Antibody (Pamrevlumab)
-
Tested applications
ELISA
-
Species reactivity
Human CCN2 / CTGF
-
Isotype
IgG1
-
Preparation
Recombinant expression and purified from CHO cells.
-
Clonality
Monoclonal
-
Formulation
0.1 M Pro-Ac, 20 mM Arg, pH 5.0
-
Storage instructions
-80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
-
Validations
SDS-PAGE
Anti-CCN2 / CTGF Antibody (pamrevlumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
SEC-HPLC
The purity of Anti-CCN2 / CTGF Antibody (pamrevlumab) is 100%, determined by SEC-HPLC.
Bioactivity: ELISA
Immobilized human CTGF His at 2 ug/mL can bind Anti-CCN2 / CTGF Antibody (pamrevlumab), EC50=0.006105 ug/mL.
Research in vivo
Pamrevlumab inhibited the tumor growth of COLO205 on Balb/c nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 39% at 40 mpk at D31.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"