Pamrevlumab reference antibody

Cat.#: 176847

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Product Information

  • Product Name
    Pamrevlumab reference antibody
  • Documents
  • Description
    Anti-CCN2 / CTGF Antibody (Pamrevlumab)
  • Tested applications
    ELISA
  • Species reactivity
    Human CCN2 / CTGF
  • Isotype
    IgG1
  • Preparation
    Recombinant expression and purified from CHO cells.
  • Clonality
    Monoclonal
  • Formulation
    0.1 M Pro-Ac, 20 mM Arg, pH 5.0
  • Storage instructions
    -80°C for 2 years under sterile conditions; -20°C for 1 year under sterile conditions; Avoid repeated freeze-thaw cycles.
  • Validations

    SDS-PAGE

    SDS-PAGE

    Anti-CCN2 / CTGF Antibody (pamrevlumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.

    SEC-HPLC

    SEC-HPLC

    The purity of Anti-CCN2 / CTGF Antibody (pamrevlumab) is 100%, determined by SEC-HPLC.

    Bioactivity: ELISA

    Bioactivity: ELISA

    Immobilized human CTGF His at 2 ug/mL can bind Anti-CCN2 / CTGF Antibody (pamrevlumab), EC50=0.006105 ug/mL.

    Research in vivo

    Research in vivo

    Pamrevlumab inhibited the tumor growth of COLO205 on Balb/c nude mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 39% at 40 mpk at D31.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"