PAK6 Polyclonal Antibody

Cat.#: 164412

Special Price 290.3 USD

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Product Information

  • Product Name
    PAK6 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to PAK6
  • Tested applications
    WB, IHC, IF
  • Species reactivity
    Human
  • Alternative names
    PAK6 antibody; PAK5 antibody; p21 activated kinase 6 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: A synthetic Peptide of human PAK6
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, pH7.3.
  • Storage instructions
    Store at 4℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:500 - 1:1000
    IHC 1:20 - 1:50
    IF 1:20 - 1:50
  • Validations

    Western blot - PAK6 Polyclonal Antibody

    Western blot - PAK6 Polyclonal Antibody

    Western blot analysis of extracts of A-431 cells, using PAK6 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.

  • Background
    Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"