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Product Name
PACSIN2 Polyclonal Antibody
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Description
Polyclonal antibody to PACSIN2
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Tested applications
WB, IHC, IF
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Species reactivity
Human, Mouse
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Alternative names
PACSIN2 antibody; SDPII antibody; protein kinase C and casein kinase substrate in neurons 2 antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: A synthetic peptide of human PACSIN2
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, pH7.3.
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Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
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Applications
WB 1:200 - 1:1000
IHC 1:50 - 1:200
IF 1:20 - 1:50 -
Validations
Western blot - PACSIN2 Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using PACSIN2 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
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Background
Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"