p504S,AMACR antibody

p504S,AMACR antibody

• DataSheet
• Material Safety Data Sheets (MSDS)

p504S,AMACR Mouse Monoclonal antibody. Positive WB detected in HEK-293 cells. Observed molecular weight by Western-blot: 42kd

ELISA, WB

human, mouse; other species not tested.

AMACR antibody; RACE antibody; p504S antibody; CBAS4 antibody; alpha methylacyl CoA racemase antibody

Mouse IgG1

This antibody was obtained by immunization of p504S,AMACR recombinant protein (Accession Number: NM_203382). Purification method: Protein G purified.

Monoclonal

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

Store at -20℃. DO NOT ALIQUOT

AMACR(Alpha-methylacyl-CoA racemase) belongs to the CaiB/BaiF CoA-transferase family. It is a mitochondrial and peroxisomal enzyme that catalyzes the conversion of 2R stereoisomers of phytanic and pristanic acid to their S counterparts. AMACR has previously been shown to be a highly sensitive marker for colorectal and clinically localized prostate cancer (PCa). However, AMACR expression is down-regulated at the transcript and protein level in hormone-refractory metastatic PCa, suggesting a hormone-dependent expression of AMACR(PMID:12213712). It has 3 isoforms produced by alternative splicing. Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency (AMACRD) and congenital bile acid synthesis defect type 4 (CBAS4).