P4HA1 antibody

Cat.#: 107444

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    P4HA1 antibody
  • Documents
  • Description
    P4HA1 Mouse Monoclonal antibody. Positive IHC detected in human breast cancer tissue, human testis tissue. Positive WB detected in PC-3 cells, HEK-293 cells. Observed molecular weight by Western-blot: 61 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    4 PH alpha 1 antibody; P4HA antibody; P4HA1 antibody
  • Immunogen
  • Isotype
    Mouse IgG1
  • Preparation
    This antibody was obtained by immunization of P4HA1 recombinant protein (Accession Number: NM_001142595). Purification method: Protein G purified.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107444(P4HA1 antibody) at dilution of 1:1000

    PC-3 cells were subjected to SDS PAGE followed by western blot with Catalog No:107444(P4HA1 antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:107444(P4HA1 Antibody) at dilution of 1:50

    Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:107444(P4HA1 Antibody) at dilution of 1:50

    Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:107444(P4HA1 Antibody) at dilution of 1:50

    Immunohistochemistry of paraffin-embedded human breast cancer slide using Catalog No:107444(P4HA1 Antibody) at dilution of 1:50

  • Background
    P4HA1(Prolyl 4-hydroxylase subunit alpha-1) is also named as P4HA and belongs to the P4HA family ,which play a central role in collagen synthesis. P4HA1 catalyzes the post-translational formation of 4-hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins. The gene encodes a polypeptide of 517 amino acid residues and a signal peptide of 17 amino acids and the full length protein has two glycosylation sites(uniprot). It can exsit as a heteromer, dimer or tetramer(GENATLAS). P4HA1 has 3 isoforms produced by alternative splicing with the molecular weight of 61 kDa, 61 kDa and 59 kDa. This antibody is specific to P4HA1.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"