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Product Name
P-selectin antibody
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Description
P-selectin Rabbit Polyclonal antibody. Positive IHC detected in human lung cancer tissue.
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Tested applications
ELISA, IHC
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Species reactivity
Human; other species not tested.
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Alternative names
CD62 antibody; CD62P antibody; FLJ45155 antibody; GMP 140 antibody; GMP140 antibody; GMRP antibody; Granule membrane protein 140 antibody; GRMP antibody; LECAM3 antibody; P selectin antibody; PADGEM antibody; PSEL antibody; P-selectin antibody; SELP antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of P-selectin recombinant protein (Accession Number: XM_005245438). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
IHC: 1:20-1:200
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Validations
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:114298(SELP antibody) at dilution of 1:50 (under 10x lens)
Immunohistochemical of paraffin-embedded human lung cancer using Catalog No:114298(SELP antibody) at dilution of 1:50 (under 40x lens)
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Background
P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"